B-Glucuronidase

 

For enzymatic hydrolysis prior to analysis of various drugs-of-abuse

 

B-Glucuronidase is found in tissue extracts of mammals and other vertebrates, digestive juices of snails, mollusks, plants and bacteria. 

B-Glucuronidase is a structural protein of the endoplasmic reticulum. 

This enzyme catalyzes the hydrolysis of B-D-glucuronides and also the transfer of glucuronly radicals to acceptor alcohols.

Our laboratory test results show performance of X-Link’s abalone source to be identical to helix palmate, for benzodiazepine.

Literature reports B-glucuronidase being used for benzodiazepines¹,  codeine, heroin, morphine², cannabinoids and mtabolites³.

The viscosity of X-Link’s glucuronidase solution is compatible for use with auto samplers.

B-Glucuronidase hydrolyzes according to the following reaction:

 

                                                            B-Glucuronidase

B-D-Glucuronide + H₂O ^_____> Alcohol + D-Glucuronate

 

Source:                       Abalone

Form:                          1 mg to 1 ml solution

Concentration:           >100,000 units/ml

Stablility:                     Stable for 1 year at 4°C

 

 

Product	Catalog#	Qty	Price (US)
Beta-Glucuronidase 1 mg/ml solution in distilled water. >100,000 units/ml	125-15-10	2 ml	$44.00
		5 ml	$80.00
		10 ml	$125.00
		25 ml	$285.00
		50 ml	$540.00

 

 

 

 

 

 

 

 

 

 

 

 

References:

1.  Needleman, S.B.; et al. Forensic Sci. Int. 1995, 73, 49.

2.  Zezulak, M.; et al. J Forensic ci. 1993, 38, 1275.

3.  Kemp, P.M.; et al. J Anal. Toxicol. 1995, 19, 285.